Tandem AN—AN reactions in the synthesis of 1H-pyrrolo[3,2-e]-1,2,4-triazines and products of their oxidative transformations

Tandem AN—AN reactions in the synthesis of 1H-pyrrolo[3,2-e]-1,2,4-triazines and products of their oxidative transformations / V. N. Charushin, N. N. Mochul`skaya, A. A. Andreiko, M. I. Kodess, I. A. Litvinov, O. G. Sinyashin, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2003. - Vol. 52, № 8. - P. 1740-1749.

Документ доступен в ЦНБ УрО РАН:

Нет

Год:

2003

Связанные персоналии:

Нет

Вид издания:

статья из журнала

Коллекции:

Нет

h1

Публичные страницы

Сканированный текст не найден

Аннотация

The reactions of 3-aryl-1,2,4-triazines with -aminovinyl ketones or ethyl -aminocrotonates in acetic anhydride at room temperature afforded cyclic products of the tandem nucleophilic addition, viz., 3a,4,7,7a-tetrahydro-1H-pyrrolo[3,2-e]-1,2,4-triazines, in good yields. Under oxidative conditions, the latter compounds underwent the pyrrole-ring opening under the action of potassium permanganate to form the corresponding triazinones and were transformed into thriazolyl-substituted pyridines under the action of selenious acid.