Is up-regulation gene expression of the certain genes during the viral respiratory tract infection would have any influence in pathogenesis of the SAR-CoV-2 infection?

Is up-regulation gene expression of the certain genes during the viral respiratory tract infection would have any influence in pathogenesis of the SAR-CoV-2 infection? / K. Shinwari, G. Liu, M. A, Bolkov [et al.] // Acta Medica Iranica. - 2020. - Vol. 58, № 5. - P. 246-248.