Proliferativeresponse of lymphocyte to pokeweed mitogen depends on the concentration of endogenous cortisol in the early post-traumatic period in patients with penetrating eye injury

Proliferativeresponse of lymphocyte to pokeweed mitogen depends on the concentration of endogenous cortisol in the early post-traumatic period in patients with penetrating eye injury / V. A. Chereshnev, Yu. I. Shilov , T. V. Gavrilova [et al.] // Bulletin of experimental biology and medicine. - 2012. - Vol. 153, № 5. - P. 722-725. - Bibliogr. : p. 724-725 (15 ref.).

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2012

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Аннотация

The intensity of lymphocyte proliferation in response to pokeweed mitogen depends on cortisol level in the peripheral blood in the early post-traumatic period of penetrating eye injury. Lymphocyte proliferation in 72- and 96-h cultures from patients with high levels of endo genous hormone was suppressed. In 120-h cultures, the intensity of proliferation remains unchanged. Lymphocyte blast transformation was increased in 120-h cultures from patients with normal cortisol concentration and remained unchanged in case of low cortisol level Доп. точки доступа: